Magnesium Bis-Glycinate - For Calming and Sleep - Lab Tested and Pure
- Lab testedThird-party, every batch
- Small-batch promiseSmall runs, never mass-produced
- Free U.S. shippingOn orders over $100
- 4.98★ · 1,239 reviewsVerified by Judge.me
This is the form that got its own trial. In 2025 a randomized, double-blind, placebo-controlled study gave adults who reported sleeping poorly 250 mg of elemental magnesium a day as bis-glycinate; their sleep-difficulty scores fell further than placebo. Same chelate, in a pork-free capsule.
A highly bioavailable form of magnesium bis-glycinate, formulated to support relaxation, calmness, and nighttime wellness. Each capsule provides approximately 150 mg of bioavailable magnesium. 100 or 200 capsules.
- Lab Tested
- Chelated Form
- USP Grade Capsule
- Pork-Free Capsule
Why people use it
- Magnesium is a cofactor. 3,751 human proteins bind magnesium (the human magnesome), including the ones that build ATP and the ones that let muscle and nerve tissue work normally.
- Glycine is the carrier. In a bis-glycinate chelate the magnesium is bound to two glycine molecules. Glycine comes along with the mineral, which is part of why people place this form at night.
- Built for the evening. Malate goes in the morning and afternoon; this one goes with dinner or before bed. Same mineral, different slot.
- Studied on this exact form. A 2025 randomized, double-blind, placebo-controlled trial gave adults reporting poor sleep 250 mg of elemental magnesium a day as bis-glycinate for four weeks. Self-reported sleep-difficulty scores fell more than placebo.
- Supports a calm wind-down. The reason most people reach for magnesium after a long day of tension, training, or screens.
- What people report. Customer feedback highlights support for relaxation, improved sleep quality, and a sense of calm. May be used in the evening to support relaxation, calmness, and restful nights.
What you're getting
The label lists approximately 150 mg of magnesium per capsule.
| Serving | Magnesium (label lists) |
|---|---|
| 1 capsule | ~150 mg |
Count every source together: capsules, lotions, baths, electrolytes.
How to use
- For best results, take Magnesium Bis-Glycinate in the late afternoon, with dinner, or before bed.
- We recommend starting with one capsule and adjusting gradually based on individual tolerance and needs.
- Do not exceed the recommended serving size.
- Keep this one after mid-afternoon; use Magnesium Malate for the daytime half.
- Total your magnesium across everything you use, not just this bottle.
Sourcing & making
Lab-tested magnesium bis-glycinate, encapsulated in lab-tested USP-grade pork-free bovine gelatin. Two ingredients on the label because two is what's in the bottle.
Full ingredients
- 24% Lab-Tested Magnesium Bis-Glycinate (Potent & Pure)
- Lab-Tested USP Grade Pork-Free Bovine Capsule
Who it's for
- People who want magnesium in an evening routine rather than a daytime one
- Anyone already taking a daytime magnesium and looking for the other half of a split-dose plan
Testing & quality
Every product is lab tested. Certificates of analysis on request, about a 2-week turnaround; email us with your lot number.
The research behind the ingredients
Published research on the ingredients in this product, for education. These studies were not conducted on this product.
Magnesium bis-glycinate
Magnesium bisglycinate sleep trial, 2025
Nature and Science of Sleep · 2025 · RCT · n=155 randomized (134 completed)
In a 4-week randomized, double-blind, placebo-controlled trial of 155 healthy adults reporting poor sleep, 250 mg/day of elemental magnesium as magnesium bisglycinate lowered Insomnia Severity Index scores more than placebo (−3.9 vs −2.3, p = 0.049) with a small effect size.
Magnesium
Magnesium sleep trial in older adults, 2012
Journal of Research in Medical Sciences · 2012 · RCT · n=46
In a double-blind placebo-controlled trial of 46 older adults, 500 mg magnesium daily for 8 weeks increased sleep time, sleep efficiency and serum melatonin and lowered serum cortisol compared with placebo.
Magnesium
Magnesium and subjective stress review, 2017
Nutrients · 2017 · systematic review · n=18 studies
A systematic review of 18 human studies found consistent directional signals that magnesium supplementation improves subjective measures of mild anxiety and stress, and called for larger, better-standardized trials to size the effect.
Magnesium
The human “magnesome”: detecting magnesium binding sites on human proteins
BMC Bioinformatics · 2012 · computational proteome-wide analysis
A proteome-wide computational analysis annotating magnesium binding sites across the human proteome. Using 251 structural clusters as templates, the authors identified 3,751 human proteins carrying putative magnesium binding sites - about 13,689 binding residues in all - and called that set the human magnesome.
Evidence note: Strong for this exact form: a 2025 randomized, double-blind, placebo-controlled trial used magnesium bisglycinate itself, backed by an older magnesium RCT on sleep architecture. Effect sizes are modest, and the wider stress and mood literature is still building toward larger, better-powered trials.
FAQ
Why bis-glycinate for the evening?
The chelate is the reason. Magnesium is bound to two glycine molecules, so glycine rides in with the mineral, and glycine is an amino acid the body uses in its own wind-down chemistry. It is also the form that got its own randomized sleep trial. That combination is why we put it after mid-afternoon.
What does the sleep research actually show?
One 2025 randomized, placebo-controlled trial, 155 adults reporting poor sleep, 250 mg of elemental magnesium daily as bis-glycinate for four weeks. Sleep-difficulty scores fell more than placebo.
Why evening for this one and daytime for malate?
Time of day, not strength. Both deliver elemental magnesium. Glycine is the carrier here and it suits a wind-down; malic acid is part of the cycle cells use to make energy, so that one goes earlier. Split them and you cover the whole day without one big dose.
Can I take it with the malate?
Many people do. Add up the elemental magnesium across everything, including baths, lotions, and electrolyte blends.
Which bottle size makes sense?
Both bottles hold the same capsule; the 200 is the refill size. Start with the 100 if you have not used this form before.
What do people notice?
Customer feedback highlights support for relaxation, improved sleep quality, and a sense of calm. Individual results may vary.
Pairs well with
- Magnesium Malate — the daytime form, the other half of the split dose
- Bomb Bath Salts — a magnesium soak for the same end of the day
- Salt of Life — high-mineral, high-electrolyte sea salt with every meal
Cautions
- Too much magnesium at once may cause digestive discomfort. We encourage responsible use.
- Consult your healthcare professional before use if pregnant, nursing, taking medication, or have a medical condition.
- If considering this product for someone under 18, seek guidance from a qualified practitioner.
- Do not exceed the recommended serving size.
- Contains bovine gelatin (capsule).
- Store in a cool, dry place. Best if used within 12 months of opening.
Lab Tested
Every product. COA on request, ~2 weeks.
Small Batch
Made in small batches, about as close to homemade as a capsule gets.
Nothing Hidden
Two ingredients: magnesium bis-glycinate and the capsule.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Nutrient figures are approximate reference values, not a lot-specific assay. Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or managing a health condition.
- Lab testedThird-party, every batch
- Small-batch promiseSmall runs, never mass-produced
- Free U.S. shippingOn orders over $100
- 4.98★ · 1,239 reviewsVerified by Judge.me
This is the form that got its own trial. In 2025 a randomized, double-blind, placebo-controlled study gave adults who reported sleeping poorly 250 mg of elemental magnesium a day as bis-glycinate; their sleep-difficulty scores fell further than placebo. Same chelate, in a pork-free capsule.
A highly bioavailable form of magnesium bis-glycinate, formulated to support relaxation, calmness, and nighttime wellness. Each capsule provides approximately 150 mg of bioavailable magnesium. 100 or 200 capsules.
- Lab Tested
- Chelated Form
- USP Grade Capsule
- Pork-Free Capsule
Why people use it
- Magnesium is a cofactor. 3,751 human proteins bind magnesium (the human magnesome), including the ones that build ATP and the ones that let muscle and nerve tissue work normally.
- Glycine is the carrier. In a bis-glycinate chelate the magnesium is bound to two glycine molecules. Glycine comes along with the mineral, which is part of why people place this form at night.
- Built for the evening. Malate goes in the morning and afternoon; this one goes with dinner or before bed. Same mineral, different slot.
- Studied on this exact form. A 2025 randomized, double-blind, placebo-controlled trial gave adults reporting poor sleep 250 mg of elemental magnesium a day as bis-glycinate for four weeks. Self-reported sleep-difficulty scores fell more than placebo.
- Supports a calm wind-down. The reason most people reach for magnesium after a long day of tension, training, or screens.
- What people report. Customer feedback highlights support for relaxation, improved sleep quality, and a sense of calm. May be used in the evening to support relaxation, calmness, and restful nights.
What you're getting
The label lists approximately 150 mg of magnesium per capsule.
| Serving | Magnesium (label lists) |
|---|---|
| 1 capsule | ~150 mg |
Count every source together: capsules, lotions, baths, electrolytes.
How to use
- For best results, take Magnesium Bis-Glycinate in the late afternoon, with dinner, or before bed.
- We recommend starting with one capsule and adjusting gradually based on individual tolerance and needs.
- Do not exceed the recommended serving size.
- Keep this one after mid-afternoon; use Magnesium Malate for the daytime half.
- Total your magnesium across everything you use, not just this bottle.
Sourcing & making
Lab-tested magnesium bis-glycinate, encapsulated in lab-tested USP-grade pork-free bovine gelatin. Two ingredients on the label because two is what's in the bottle.
Full ingredients
- 24% Lab-Tested Magnesium Bis-Glycinate (Potent & Pure)
- Lab-Tested USP Grade Pork-Free Bovine Capsule
Who it's for
- People who want magnesium in an evening routine rather than a daytime one
- Anyone already taking a daytime magnesium and looking for the other half of a split-dose plan
Testing & quality
Every product is lab tested. Certificates of analysis on request, about a 2-week turnaround; email us with your lot number.
The research behind the ingredients
Published research on the ingredients in this product, for education. These studies were not conducted on this product.
Magnesium bis-glycinate
Magnesium bisglycinate sleep trial, 2025
Nature and Science of Sleep · 2025 · RCT · n=155 randomized (134 completed)
In a 4-week randomized, double-blind, placebo-controlled trial of 155 healthy adults reporting poor sleep, 250 mg/day of elemental magnesium as magnesium bisglycinate lowered Insomnia Severity Index scores more than placebo (−3.9 vs −2.3, p = 0.049) with a small effect size.
Magnesium
Magnesium sleep trial in older adults, 2012
Journal of Research in Medical Sciences · 2012 · RCT · n=46
In a double-blind placebo-controlled trial of 46 older adults, 500 mg magnesium daily for 8 weeks increased sleep time, sleep efficiency and serum melatonin and lowered serum cortisol compared with placebo.
Magnesium
Magnesium and subjective stress review, 2017
Nutrients · 2017 · systematic review · n=18 studies
A systematic review of 18 human studies found consistent directional signals that magnesium supplementation improves subjective measures of mild anxiety and stress, and called for larger, better-standardized trials to size the effect.
Magnesium
The human “magnesome”: detecting magnesium binding sites on human proteins
BMC Bioinformatics · 2012 · computational proteome-wide analysis
A proteome-wide computational analysis annotating magnesium binding sites across the human proteome. Using 251 structural clusters as templates, the authors identified 3,751 human proteins carrying putative magnesium binding sites - about 13,689 binding residues in all - and called that set the human magnesome.
Evidence note: Strong for this exact form: a 2025 randomized, double-blind, placebo-controlled trial used magnesium bisglycinate itself, backed by an older magnesium RCT on sleep architecture. Effect sizes are modest, and the wider stress and mood literature is still building toward larger, better-powered trials.
FAQ
Why bis-glycinate for the evening?
The chelate is the reason. Magnesium is bound to two glycine molecules, so glycine rides in with the mineral, and glycine is an amino acid the body uses in its own wind-down chemistry. It is also the form that got its own randomized sleep trial. That combination is why we put it after mid-afternoon.
What does the sleep research actually show?
One 2025 randomized, placebo-controlled trial, 155 adults reporting poor sleep, 250 mg of elemental magnesium daily as bis-glycinate for four weeks. Sleep-difficulty scores fell more than placebo.
Why evening for this one and daytime for malate?
Time of day, not strength. Both deliver elemental magnesium. Glycine is the carrier here and it suits a wind-down; malic acid is part of the cycle cells use to make energy, so that one goes earlier. Split them and you cover the whole day without one big dose.
Can I take it with the malate?
Many people do. Add up the elemental magnesium across everything, including baths, lotions, and electrolyte blends.
Which bottle size makes sense?
Both bottles hold the same capsule; the 200 is the refill size. Start with the 100 if you have not used this form before.
What do people notice?
Customer feedback highlights support for relaxation, improved sleep quality, and a sense of calm. Individual results may vary.
Pairs well with
- Magnesium Malate — the daytime form, the other half of the split dose
- Bomb Bath Salts — a magnesium soak for the same end of the day
- Salt of Life — high-mineral, high-electrolyte sea salt with every meal
Cautions
- Too much magnesium at once may cause digestive discomfort. We encourage responsible use.
- Consult your healthcare professional before use if pregnant, nursing, taking medication, or have a medical condition.
- If considering this product for someone under 18, seek guidance from a qualified practitioner.
- Do not exceed the recommended serving size.
- Contains bovine gelatin (capsule).
- Store in a cool, dry place. Best if used within 12 months of opening.
Lab Tested
Every product. COA on request, ~2 weeks.
Small Batch
Made in small batches, about as close to homemade as a capsule gets.
Nothing Hidden
Two ingredients: magnesium bis-glycinate and the capsule.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Nutrient figures are approximate reference values, not a lot-specific assay. Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or managing a health condition.
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